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1

Four-week cold acclimation in adult humans shifts uncoupling thermogenesis from skeletal muscles to brown adipose tissue

Blondin, Denis P., Daoud, Amani, Taylor, Taryn, Tingelstad, Hans C., Bézaire, Véronic, Richard, Denis, Carpentier, André C., Taylor, Albert W., Harper, Mary-Ellen, Aguer, Céline, Haman, François

Journal:

The Journal of Physiology

Année:

2017

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2017

2

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

Enerbäck, Sven, Jacobsson, Anders, Simpson, Elizabeth M., Guerra, Carmen, Yamashita, Hitoshi, Harper, Mary-Ellen, Kozak, Leslie P.

Journal:

Année:

1997

Fichier:

PDF, 2.33 MB

1997

3

Uncoupling proteins and the control of mitochondrial reactive oxygen species production

Ryan J. Mailloux, Mary-Ellen Harper

Journal:

Free Radical Biology and Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 571 KB

english, 2011

4

Influence of mitochondrial membrane fatty acid composition on proton leak and H2O2 production in liver

Jon J. Ramsey, Mary-Ellen Harper, Stephen J. Humble, Edward K. Koomson, Jesmon J. Ram, Lisa Bevilacqua, Kevork Hagopian

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Année:

2005

Langue:

english

Fichier:

PDF, 231 KB

english, 2005

5

Enhanced glucose homeostasis in BHE/cdb rats with mutated ATP synthase

Harasym, Anne C., Thrush, A. Brianne, Harper, Mary-Ellen, Wright, David C., Chan, Catherine B.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 496 KB

english, 2013

6

Implications of mitochondrial uncoupling in skeletal muscle in the development and treatment of obesity

Thrush, A. Brianne, Dent, Robert, McPherson, Ruth, Harper, Mary-Ellen

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 387 KB

english, 2013

7

Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program

Khacho, Mireille, Clark, Alysen, Svoboda, Devon S., Azzi, Joelle, MacLaurin, Jason G., Meghaizel, Cynthia, Sesaki, Hiromi, Lagace, Diane C., Germain, Marc, Harper, Mary-Ellen, Park, David S., Slack, R

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 7.09 MB

english, 2016

8

Factors affecting weight loss variability in obesity

Dent, Robert, McPherson, Ruth, Harper, Mary-Ellen

Journal:

Année:

2020

Fichier:

PDF, 2.88 MB

2020

9

Role of Glutathione in Cancer: From Mechanisms to Therapies

Kennedy, Luke, Sandhu, Jagdeep K., Harper, Mary-Ellen, Cuperlovic-Culf, Miroslava

Journal:

Année:

2020

Fichier:

PDF, 2.99 MB

2020

10

Comparison of the subcellular distribution of G-proteins in hepatocytes in situ and in primary cultures

Monique Cadrin, Norma McFarlane-Anderson, Mary-Ellen Harper, Johanna Gaffield, Nicole Bégin-Heick

Journal:

Journal of Cellular Biochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 866 KB

english, 1996

11

Mutated ATP synthase induces oxidative stress and impaired insulin secretion in β-cells of female BHE/cdb rats

Monique C. Saleh, Zahra Fatehi-Hassanabad, Rennian Wang, Rodolpho Nino-Fong, Dorota W. Wadowska, Glenda M. Wright, Mary-Ellen Harper, Catherine B. Chan

Journal:

Diabetes/Metabolism Research and Reviews

Année:

2008

Langue:

english

Fichier:

PDF, 815 KB

english, 2008

12

Sympathetic nervous dysregulation in the absence of systolic left ventricular dysfunction in a rat model of insulin resistance with hyperglycemia

James T Thackeray, Jerry Radziuk, Mary-Ellen Harper, Erik J Suuronen, Kathryn J Ascah, Rob S Beanlands, Jean N DaSilva

Journal:

Cardiovascular Diabetology

Année:

2011

Langue:

english

Fichier:

PDF, 1009 KB

english, 2011

13

Cellular metabolism as a basis for immune privilege

M Karen Newell, Elizabeth Villalobos-Menuey, Susan C Schweitzer, Mary-Ellen Harper, Robert E Camley

Journal:

Journal of Immune Based Therapies and Vaccines

Année:

2006

Langue:

english

Fichier:

PDF, 721 KB

english, 2006

14

Gene expression profiling in whole blood identifies distinct biological pathways associated with obesity

Sujoy Ghosh, Robert Dent, Mary-Ellen Harper, Shelby A Gorman, Joan S Stuart, Ruth McPherson

Journal:

BMC Medical Genomics

Année:

2010

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2010

15

Ablation of LMO4 in glutamatergic neurons impairs leptin control of fat metabolism

Xun Zhou, Mariana Gomez-Smith, Zhaohong Qin, Philippe M. Duquette, Arturo Cardenas-Blanco, Punarpreet S. Rai, Mary-Ellen Harper, Eve C. Tsai, Hymie Anisman, Hsiao-Huei Chen

Journal:

Cellular and Molecular Life Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 608 KB

english, 2012

16

Does the Oxidative/Glycolytic Ratio Determine Proliferation or Death in Immune Recognition?

M. KAREN NEWELL, MARY-ELLEN HARPER, KAREN FORTNER, JULIE DESBARATS, ALICIA RUSSO, SALLY A. HUBER

Journal:

Annals of the New York Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 378 KB

english, 1999

17

Peroxisome Proliferator-activated Receptor γ 2 and Acyl-CoA Synthetase 5 Polymorphisms Influence Diet Response

Kristi B. Adamo, Robert Dent, Carl D. Langefeld, Miranda Cox, Kathryn Williams, Kevin M. Carrick, Joan S. Stuart, Scott S. Sundseth, Mary-Ellen Harper, Ruth McPherson, Frédérique Tesson

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 107 KB

english, 2007

18

Absence of uncoupling protein-3 leads to greater activation of an adenine nucleotide translocase-mediated proton conductance in skeletal muscle mitochondria from calorie restricted mice

Lisa Bevilacqua, Erin L. Seifert, Carmen Estey, Martin F. Gerrits, Mary-Ellen Harper

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

2010

Langue:

english

Fichier:

PDF, 771 KB

english, 2010

19

Calorie restriction in mice overexpressing UCP3: Evidence that prior mitochondrial uncoupling alters response

Carmen Estey, Erin L. Seifert, Céline Aguer, Cynthia Moffat, Mary-Ellen Harper

Journal:

Experimental Gerontology

Année:

2012

Langue:

english

Fichier:

PDF, 885 KB

english, 2012

20

The Physiological Implications for Controlling Uncoupling Proteins 2 and 3 by Glutathionylation

Ryan J. Mailloux, Mary-Ellen Harper

Journal:

Free Radical Biology and Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 54 KB

english, 2011

21

Restriction of energy intake, energy expenditure, and aging

Jon J Ramsey, Mary-Ellen Harper, Richard Weindruch

Journal:

Free Radical Biology and Medicine

Année:

2000

Langue:

english

Fichier:

PDF, 303 KB

english, 2000

22

Mitochondrial proticity and ROS signaling: lessons from the uncoupling proteins

Ryan J. Mailloux, Mary-Ellen Harper

Journal:

Trends in Endocrinology & Metabolism

Année:

2012

Langue:

english

Fichier:

PDF, 337 KB

english, 2012

23

Altered Brown Adipose Tissue and Na,K Pump Activities During Diet-Induced Obesity and Weight Loss in Rats

Dr. Mary-Ellen Harper, John Patrick, Jean Himms-Hagen

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 1.30 MB

english, 1993

24

Overexpression of UCP-3 in Skeletal Muscle of Mice Results in Increased Expression of Mitochondrial Thioesterase mRNA

Gary B.T. Moore, Jean Himms-Hagen, Mary-Ellen Harper, John C. Clapham

Journal:

Biochemical and Biophysical Research Communications

Année:

2001

Langue:

english

Fichier:

PDF, 84 KB

english, 2001

25

Proportional activation coefficients during stimulation of oxidative phosphorylation by lactate and pyruvate or by vasopressin

Bernard Korzeniewski, Mary-Ellen Harper, Martin D. Brand

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

1995

Langue:

english

Fichier:

PDF, 769 KB

english, 1995

26

Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1α

Anthony Scimè, Guillaume Grenier, Michael S. Huh, Mark A. Gillespie, Lisa Bevilacqua, Mary-Ellen Harper, Michael A. Rudnicki

Journal:

Cell Metabolism

Année:

2005

Langue:

english

Fichier:

PDF, 832 KB

english, 2005

27

Mitochondrial uncoupling proteins as potential targets for pharmacological agents

Mary-Ellen Harper, Martin F Gerrits

Journal:

Current Opinion in Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 115 KB

english, 2004

28

Mitochondrial efficiency: lessons learned from transgenic mice

Mary-Ellen Harper, Jean Himms-Hagen

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

2001

Langue:

english

Fichier:

PDF, 195 KB

english, 2001

29

Percent relative cumulative frequency analysis in indirect calorimetry: application to studies of transgenic mice

Riachi, Marc, Himms-Hagen, Jean, Harper, Mary-Ellen

Journal:

Canadian Journal of Physiology and Pharmacology

Année:

2004

Fichier:

PDF, 246 KB

2004

30

Glutathionylation of UCP2 sensitizes drug resistant leukemia cells to chemotherapeutics

Aline Pfefferle, Ryan J. Mailloux, Cyril Nii-Klu Adjeitey, Mary-Ellen Harper

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2013

31

Skeletal muscle mitochondrial energetics in obesity and type 2 diabetes mellitus: Endocrine aspects

Céline Aguer, Mary-Ellen Harper

Journal:

Best Practice & Research Clinical Endocrinology & Metabolism

Année:

2012

Langue:

english

Fichier:

PDF, 713 KB

english, 2012

32

Impaired adaptability of in vivo mitochondrial energetics to acute oxidative insult in aged skeletal muscle

Siegel, Michael P., Wilbur, Tim, Mathis, Mark, Shankland, Eric G., Trieu, Atlas, Harper, Mary-Ellen, Marcinek, David J.

Journal:

Mechanisms of Ageing and Development

Année:

2012

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2012

33

Thyroid Hormone Effects on Mitochondrial Energetics

Harper, Mary-Ellen, Seifert, Erin L.

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 3.22 MB

english, 2008

34

M ITOCHONDRIAL U NCOUPLING P ROTEINS IN E NERGY E XPENDITURE

Kozak, Leslie P., Harper, Mary-Ellen

Journal:

Annual Review of Nutrition

Année:

2000

Langue:

english

Fichier:

PDF, 568 KB

english, 2000

35

Chronic AMPK activity dysregulation produces myocardial insulin resistance in the human Arg302Gln-PRKAG2 glycogen storage disease mouse model

Stephanie L Thorn, Michael H Gollob, Mary-Ellen Harper, Rob S Beanlands…

Journal:

EJNMMI Research

Année:

2013

Langue:

english

Fichier:

PDF, 851 KB

english, 2013

36

Unearthing the secrets of mitochondrial ROS and glutathione in bioenergetics

Mailloux, Ryan J., McBride, Skye L., Harper, Mary-Ellen

Journal:

Trends in Biochemical Sciences

Année:

2013

Langue:

english

Fichier:

PDF, 1009 KB

english, 2013

37

Increased proton leak and SOD2 expression in myotubes from obese non-diabetic subjects with a family history of type 2 diabetes

Aguer, Céline, Pasqua, Melissa, Thrush, A. Brianne, Moffat, Cynthia, McBurney, Michael, Jardine, Karen, Zhang, Rui, Beauchamp, Brittany, Dent, Robert, McPherson, Ruth, Harper, Mary-Ellen

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Année:

2013

Langue:

english

Fichier:

PDF, 525 KB

english, 2013

38

Genetic Deficiency for Proprotein Convertase 2 (PC2) in Mice is Protective form Age and Diet-induced Obesity.

Anini, Younes, Mayne, Janice, Sirois, Francine, Gagnon, Jeffrey, Chen, Andrew, Kaefer, Nadine, Harper,, Mary-Ellen, Chrétien, Michel, Mbikay, Majambu

Journal:

Canadian Journal of Diabetes

Année:

2008

Langue:

english

Fichier:

PDF, 231 KB

english, 2008

39

In memoriam

Anini, Younes, Mayne, Janice, Sirois, Francine, Gagnon, Jeffrey, Chen, Andrew, Kaefer, Nadine, Harper,, Mary-Ellen, Chrétien, Michel, Mbikay, Majambu

Journal:

Journal of Endodontics

Année:

1986

Langue:

english

Fichier:

PDF, 170 KB

english, 1986

40

Investigating The Metabolic Basis for Weight loss Variability in Obese Humans

Thrush, A. Brianne, Antoun, Ghadi, Boushel, Robert, Doucet, Éric, Imbeault, Pascal, McPherson, Ruth, Dent, Robert, Harper, Mary-Ellen

Journal:

Canadian Journal of Diabetes

Année:

2013

Langue:

english

Fichier:

PDF, 53 KB

english, 2013

41

Impairment of Proinsulin Processing in β-Cells Exposed to Saturated Free Fatty Acid Is Dependent on Uncoupling Protein-2 Expression

Kashemsant, Narudee, Bucurescu, Septimiu, Fatehi-Hassanabad, Zahra, Harper, Mary-Ellen, Chan, Catherine B.

Journal:

Canadian Journal of Diabetes

Année:

2012

Fichier:

PDF, 1.24 MB

2012

42

ACSL5 Genotype Influences the Response of Overweight and Obese Women to Weight Loss Intervention

Rajkumar, Abishankari, Bolongo, Pierrette, Adamo, Kristi, Harper, Mary-Ellen, Rabasa-Lhoret, Remi, Doucet, Éric, Prud'homme, Denis, Tesson, Frédérique

Journal:

Canadian Journal of Diabetes

Année:

2014

Langue:

english

Fichier:

PDF, 53 KB

english, 2014

43

Hyperthyroidism stimulates mitochondrial proton leak and ATP turnover in rat hepatocytes but does not change the overall kinetics of substrate oxidation reactions

Harper, Mary-Ellen, Brand, Martin D.

Journal:

Canadian Journal of Physiology and Pharmacology

Année:

1994

Langue:

english

Fichier:

PDF, 1.24 MB

english, 1994

44

Reduced in vivo phosphodiesterase-4 response to acute noradrenaline challenge in diet-induced obese rats

Greene, Michael, Thackeray, James T., Kenk, Miran, Thorn, Stephanie L., Bevilacqua, Lisa, Harper, Mary-Ellen, Beanlands, Rob S., DaSilva, Jean N.

Journal:

Canadian Journal of Physiology and Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 287 KB

english, 2009

45

The energetic implications of uncoupling protein-3 in skeletal muscle

Costford, Sheila R., Seifert, Erin L., Bézaire, Véronic, F. Gerrits, Martin, Bevilacqua, Lisa, Gowing, Adrienne, Harper, Mary-Ellen

Journal:

Applied Physiology Nutrition and Metabolism

Année:

2007

Fichier:

PDF, 1.79 MB

2007

46

Lower Mitochondrial Proton Leak and Decreased Glutathione Redox in Primary Muscle Cells of Obese Diet-Resistant Versus Diet-Sensitive Humans

Thrush, A. Brianne, Zhang, Rui, Chen, William, Seifert, Erin L., Quizi, Jessica K., McPherson, Ruth, Dent, Robert, Harper, Mary-Ellen

Journal:

Journal of Clinical Endocrinology & Metabolism

Année:

2014

Langue:

english

Fichier:

PDF, 735 KB

english, 2014

47

The Efficiency of Cellular Energy Transduction and Its Implications for Obesity

Harper, Mary-Ellen, Green, Katherine, Brand, Martin D.

Journal:

Annual Review of Nutrition

Année:

2008

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2008

48

Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival

Khacho, Mireille, Tarabay, Michelle, Patten, David, Khacho, Pamela, MacLaurin, Jason G., Guadagno, Jennifer, Bergeron, Richard, Cregan, Sean P., Harper, Mary-Ellen, Park, David S., Slack, Ruth S.

Journal:

Nature Communications

Année:

2014

Langue:

english

Fichier:

PDF, 4.41 MB

english, 2014

49

Uncoupling Proteins: Role in Insulin Resistance and Insulin Insufficiency

B.Chan, Catherine, Harper, Mary-Ellen

Journal:

Current Diabetes Reviews

Année:

2006

Langue:

english

Fichier:

PDF, 172 KB

english, 2006

50

Invited Review: Uncoupling proteins and thermoregulation

Argyropoulos, George, Harper, Mary-Ellen

Journal:

Journal of Applied Physiology

Année:

2002

Langue:

english

Fichier:

PDF, 118 KB

english, 2002